{"id":5265,"date":"2022-05-20T17:00:50","date_gmt":"2022-05-20T08:00:50","guid":{"rendered":"http:\/\/yanomc.com\/blog_wp_system\/?p=5265"},"modified":"2022-05-23T17:35:30","modified_gmt":"2022-05-23T08:35:30","slug":"%e5%8f%97%e7%b2%be%e5%8d%b5%e3%81%ae%e7%9d%80%e5%ba%8a%e5%89%8d%e8%a8%ba%e6%96%adpgt-preimplantation-genetic-testing%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"post","link":"https:\/\/yanomc.com\/blog_wp_system\/?p=5265","title":{"rendered":"\u53d7\u7cbe\u5375\u306e\u7740\u5e8a\u524d\u8a3a\u65ad(PGT)\u306b\u3064\u3044\u3066"},"content":{"rendered":"
\u53d7\u7cbe\u5375\u306e\u7740\u5e8a\u524d\u8a3a\u65ad(PGT: Preimplantation Genetic Testing)\u306b\u3064\u3044\u3066<\/h6>\n

\u306f\u3058\u3081\u306b<\/span><\/p>\n

\u5f53\u9662\u306f\u4e0d\u80b2\u75c7\uff08\u7fd2\u6163\u6027\u6d41\u7523\uff09\u306e\u3054\u592b\u5a66\u306b\u5bfe\u3059\u308b\u691c\u67fb\u3068\u3057\u3066\u30012010\u5e74\uff08H.21\uff09\u306b\u7740\u5e8a\u524d\u8a3a\u65ad(PGD: Preimplantation Genetic Diagnosis)<\/span>\u3092\u958b\u59cb\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u5f8c\u3001\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b5\u30fc(NGS: Next Generation Sequencer)\u306b\u3088\u308b\u30b2\u30ce\u30e0(DNA)\u89e3\u6790\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u3088\u308a\u6b63\u78ba\u306a\u53d7\u7cbe\u5375\u306e\u5206\u6790\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u305d\u308c\u306b\u4f34\u3044\u3001\u7740\u5e8a\u524d\u8a3a\u65ad\u306e\u540d\u79f0\u306fPGD\u304b\u3089PGT\u306b\u5909\u308f\u308a\u3001\u5f53\u9662\u3082\u65b0\u305f\u306b\u300c\u7740\u5e8a\u524d\u8a3a\u65ad(PGT)\u5b9f\u65bd\u65bd\u8a2d\u300d\u306e\u8a8d\u53ef\u3092\u53d7\u3051\u307e\u3057\u305f(2021\u5e74\uff09\u3002<\/p>\n

 <\/p>\n

\u53d7\u7cbe\u5375\u306b\u5bfe\u3059\u308b\u7740\u5e8a\u524d\u8a3a\u65ad(PGT)\u306e\u65b9\u6cd5<\/span><\/p>\n

\u4f53\u5916\u53d7\u7cbe(IVF)\u307e\u305f\u306f\u9855\u5fae\u6388\u7cbe(ICSI)\u306b\u3088\u308a\u53d7\u7cbe\u5375\u3092\u5f97\u3066\u3001\u305d\u306e\u53d7\u7cbe\u5375\uff08\u80da\u76e4\u80de\uff09\u306e\u5916\u5074\uff08\u6804\u990a\u5916\u80da\u8449\uff09\u306e\u7d30\u80de\u3092\u6570\u500b\u63a1\u53d6\u3057\u307e\u3059\uff08\u80da\u751f\u691c\uff09\u3002\u63a1\u53d6\u3055\u308c\u305f\u7d30\u80de\u306f\u51cd\u7d50\u4fdd\u5b58\u3055\u308c\u3001\u30b2\u30ce\u30e0(DNA)\u89e3\u6790\u3092\u3059\u308b\u305f\u3081\u3001\u65e5\u672c\u7523\u79d1\u5a66\u4eba\u79d1\u5b66\u4f1a\u306b\u8a8d\u5b9a\u3055\u308c\u305f\u5916\u90e8\u306e\u691c\u67fb\u6a5f\u95a2\u3078\u63d0\u51fa\u3057\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u7740\u5e8a\u524d\u8a3a\u65ad(PGT)\u306e\u7a2e\u985e<\/span><\/p>\n

1.\u7740\u5e8a\u524d\u80da\u67d3\u8272\u4f53\u7570\u6570\u6027\u691c\u67fb: PGT-A (Aneuploidy)<\/strong><\/p>\n

\u53cd\u5fa9ART\u4e0d\u6210\u529f\u3001\u53cd\u5fa9\u7740\u5e8a\u4e0d\u5168\u3001\u53cd\u5fa9\u6d41\u7523\u306e\u60a3\u8005\u69d8\u304c\u5bfe\u8c61\u3067\u3059\u3002
\n\u6b63\u6570\u80da\uff08\u67d3\u8272\u4f53\u306e\u6570\u7684\u7570\u5e38\u306a\u3057\uff09\u3068\u5224\u5b9a\u3055\u308c\u305f\u80da\u306e\u307f\u3092\u79fb\u690d\u3059\u308b\u3053\u3068\u3067\u3001\u598a\u5a20\u7387\u306e\u5411\u4e0a\u3068\u6d41\u7523\u7387\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n

 <\/p>\n

2.\u7740\u5e8a\u524d\u80da\u67d3\u8272\u4f53\u69cb\u9020\u7570\u5e38\u691c\u67fb: PGT-SR(Structural Re-arrangement)<\/strong><\/p>\n

\u5f53\u9662\u304c\u7a4d\u6975\u7684\u306b\u884c\u306a\u3063\u3066\u304d\u305f\u691c\u67fb\u3067\u3059\u3002\u3069\u3061\u3089\u304b\u304c\u67d3\u8272\u4f53\u7570\u5e38\u3092\u6709\u3059\u308b\u30ab\u30c3\u30d7\u30eb\u3067\u306f\u5065\u5eb7\u306b\u751f\u6d3b\u3067\u304d\u308b\u5065\u5e38\u8005\u3067\u3042\u3063\u3066\u3082\u3001\u598a\u5a20\u3059\u308b\u3068\u6d41\u7523\u3092\u7e70\u308a\u8fd4\u3059\uff08\u4e0d\u80b2\uff09\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u67d3\u8272\u4f53\u7570\u5e38\u3068\u3057\u3066\u300c\u5747\u8861\u578b\u8ee2\u5ea7\u300d\u3068\u300c\u30ed\u30d0\u30fc\u30c8\u30bd\u30f3\u8ee2\u5ea7\u300d\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002
\n\u4e0d\u80b2\u75c7\u306e\u539f\u56e0\u3068\u3057\u3066\u306f\u5c11\u306a\u3044\u3067\u3059\u304c\u30014.5\uff05\u7a0b\u5ea6\u306b\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002\u598a\u5a20\u3057\u3066\u3082\u6d41\u7523\u3092\u7e70\u308a\u8fd4\u305b\u3070\u3001\u7cbe\u795e\u7684\u8ca0\u62c5\u304c\u5927\u304d\u304f\u306a\u308a\u307e\u3059\u3002\u3059\u3053\u3057\u3067\u3082\u6d41\u7523\u7387\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u3067\u7cbe\u795e\u7684\u306a\u30b5\u30dd\u30fc\u30c8\u3092\u884c\u306a\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

3.\u7740\u5e8a\u524d\u907a\u4f1d\u5b66\u7684\u691c\u67fb: PGT-M(Monogenic)<\/strong><\/p>\n

\u91cd\u7be4\u306a\u907a\u4f1d\u6027\u75be\u60a3\uff08\u30c7\u30b7\u30e3\u30f3\u30cc\u578b\u7b4b\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u75c7\u306a\u3069\u306e\u907a\u4f1d\u75c5\uff09\u306e\u767a\u75c7\u8005\u3084\u4fdd\u56e0\u8005\u304c\u691c\u67fb\u306e\u5bfe\u8c61\u3068\u306a\u308a\u307e\u3059\u3002\u53d7\u7cbe\u5375\u306e\u30b2\u30ce\u30e0(DNA)\u89e3\u6790\u3092\u3059\u308b\u3053\u3068\u3067\u3001\u305d\u306e\u75be\u60a3\u306b\u95a2\u9023\u3059\u308b\u7570\u5e38\u3092\u8abf\u3079\u307e\u3059\u3002\u300c\u547d\u306e\u9078\u629e\u300d\u306b\u95a2\u308f\u308b\u751f\u547d\u502b\u7406\u4e0a\u306e\u554f\u984c\u3067\u3042\u308a\u3001\u5f53\u9662\u304c\u5358\u72ec\u3067\u306f\u884c\u3048\u307e\u305b\u3093\u3002\u611b\u5a9b\u5927\u5b66\u9644\u5c5e\u75c5\u9662\u3068\u9023\u643a\u3057\u306a\u304c\u3089\u614e\u91cd\u306b\u884c\u306a\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u53d7\u7cbe\u5375\u306e\u7740\u5e8a\u524d\u8a3a\u65ad(PGT: Preimplantation Genetic Testing)\u306b\u3064\u3044\u3066 \u306f\u3058\u3081\u306b \u5f53\u9662\u306f\u4e0d\u80b2\u75c7\uff08\u7fd2\u6163\u6027\u6d41\u7523\uff09\u306e\u3054\u592b\u5a66\u306b\u5bfe\u3059\u308b\u691c\u67fb\u3068\u3057\u3066\u30012010\u5e74\uff08H.21\uff09\u306b\u7740\u5e8a\u524d\u8a3a\u65ad(PGD: Pre […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":""},"categories":[4,12],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=\/wp\/v2\/posts\/5265"}],"collection":[{"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5265"}],"version-history":[{"count":4,"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=\/wp\/v2\/posts\/5265\/revisions"}],"predecessor-version":[{"id":5276,"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=\/wp\/v2\/posts\/5265\/revisions\/5276"}],"wp:attachment":[{"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5265"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5265"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yanomc.com\/blog_wp_system\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5265"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}